Depo provera side effects

Depo provera side effects :
a look at Purpose, Interactions and Warnings

Depo provera (Medroxyprogesterone) is used to treat amenorrhea (the absence of menstrual periods), dysmenorrhea (painful menstruation), and abnormal bleeding from the uterus caused by hormonal imbalance. This drug also may be taken with estrogen to decrease the risk of endometrial cancer.

Medroxyprogesterone injection is used as a contraceptive. It prevents the release of eggs from the ovaries (ovulation) and thus prevents pregnancy.

Special Warning about Depo provera side effects

According to The American Society of Health-System Pharmacists (ASHP),"Progesterone or progesterone-like drugs have been used to prevent miscarriage in the first few months of pregnancy. No adequate evidence is available to show that they are effective for this purpose. Therefore, the use of medroxyprogesterone during the first 4 months of pregnancy is not recommended. Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking medroxyprogesterone, call your doctor immediately."

Depo provera side effects and interactions

It is very important that your health care professional check your progress at regular visits. This will allow your dosage to be adjusted to your changing needs, and will allow any unwanted Depo provera side effects to be detected. These visits are usually every 12 months when you are taking progestins by mouth for birth control.

If you are receiving the medroxyprogesterone injection for contraception, a physical exam is needed only every 12 months, but you need an injection every 3 months (13 weeks). If you are using the levonorgestrel implants, your doctor will want to check the area where they were placed within 30 days after they are put into or removed from your arm. After that, a visit every 12 months usually is all that is needed. Progestins may cause some people to become dizzy. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Vaginal bleeding of various amounts may occur between your regular menstrual periods during the first 3 months of use. This is not unusual and does not mean you should stop the medicine. This is sometimes called spotting when the bleeding is slight, or breakthrough bleeding when it is heavier. If this occurs, continue on your regular dosing schedule. Check with your doctor if vaginal bleeding continues for an unusually long time, if your menstrual period has not started within 45 days of your last period or you miss menstrual periods. If you suspect a pregnancy, you should call your doctor immediately.

If you are scheduled for any laboratory tests, tell your health care professional that you are taking a progestin. Progestins can change certain test results.

The following medicines might reduce the effectiveness of progestins for contraception: Aminoglutethimide (e.g., Cytadren), Carbamazepine (e.g., Tegretol), Phenobarbital, Phenytoin (e.g., Dilantin), Rifabutin (e.g., Mycobutin), Rifampin (e.g., Rifadin).

Observed Depo provera side effects

Along with its needed effects, there may be unwanted Depo provera side effects. Although not all of these Depo provera side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur:

More Commonly Observed

Changes in uterine bleeding (increased amounts of menstrual bleeding occurring at regular monthly periods; lighter uterine bleeding between menstrual periods; heavier uterine bleeding between regular monthly periods; or stopping of menstrual periods.

Less Commonly Observed

Mental depression; skin rash; unexpected or increased flow of breast milk.

Other Depo provera side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More Commonly Observed

Abdominal pain or cramping; diarrhea ; dizziness; fatigue; mild headache; mood changes; nausea; nervousness; pain or irritation at place of injection or place where implants were inserted ; swelling of face, ankles, or feet; unusual tiredness or weakness; vomiting ; weight gain.

Less Commonly Observed

Acne; breast pain or tenderness; brown spots on exposed skin, possibly long-lasting; hot flashes; loss or gain of body, facial, or scalp hair; loss of sexual desire; trouble in sleeping.

Not all of the Depo provera side effects listed above have been reported for each of these medicines, but they have been reported for at least one of them. All of the progestins are similar, so any of the above side effects may occur with any of these medicines.

After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time check with your doctor if you notice any of the following side effects: delayed return to fertility; stopping of menstrual periods; unusual menstrual bleeding (continuing) .

Other Depo provera side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Sources : The American Society of Health-System Pharmacists (ASHP) and the United States Pharmacopeia (USP)

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